Germ Spreader Challenge:
Hands-On Lesson in Germs, Glitter, and Handwashing!
Hands-On Lesson in Germs, Glitter, and Handwashing!
Looking for a science experiment that makes the invisible world of germs come to life? This memorable germ spread challenge uses glitter as pretend “germs” to show kids how quickly germs can travel from person to person and onto everyday objects. Perfect for grades 2–5 and easy to run at home, this hands-on activity visually demonstrates why handwashing is so important—and gives kids a “wow!” moment they’ll remember. Includes step-by-step instructions, science explanations, parent tips, and a free printable worksheet.
Experiment Details
- Grade Level: 2nd–5th Grade (adaptable K–8)
- Key Topics: Germs, Hygiene, Modeling, Handwashing
- Estimated Time: 20–25 minutes
- Mess Factor: Medium (but worth it!)
Purpose: To model how germs spread from person to person and object to object, and to show why handwashing is important for staying healthy.
Hypothesis: If glitter is used to represent germs, then touching objects and people will spread the glitter everywhere—just like germs do!
What You’ll Need
- Small container of fine glitter (avoid very dark colors)
- 1 tablespoon hand lotion or moisturizer
- Paper towels or tissues
- Soap and water for washing hands
- Several small objects to touch (toys, books, doorknobs, etc.)
- Clean plate or tray (to catch falling glitter)
- Optional: sticky notes to label objects

Step-by-Step Instructions
- Put about 1 tablespoon of hand lotion on your hands and rub to cover your palms and fingers evenly.
- Shake a small amount of glitter onto your hands so it sticks to the lotion. The glitter represents germs!
- Without washing your hands, touch several objects—try toys, books, a doorknob, and other household items.
- Ask a family member or friend to shake hands with you or give you a high five.
- Look closely at each object and the other person’s hands. Where has the glitter spread?
- Use a paper towel to wipe some of the objects—does the glitter transfer to the towel?
- Now wash your hands well with soap and water for at least 20 seconds. Dry your hands. Is any glitter left?
- Clean up all remaining glitter with paper towels and throw them away.

Results & Scientific Explanation
You’ll notice glitter on almost every object you touched and on other people’s hands. This shows how easily germs can spread in real life—even when we can’t see them! The hand lotion helps glitter stick, just like germs stick to our skin. Washing hands well with soap and water removes the glitter, just as it removes germs. The lesson? Handwashing really works to keep us healthy!
- Germ transfer: Germs (glitter) spread to everything you touch and to people you contact.
- Handwashing: Soap and water remove germs by lifting them from the skin and washing them away.
- Visual model: Glitter helps children “see” the invisible journey of germs—and understand the power of hygiene!
Connecting to Everyday Life
The next time someone sneezes, coughs, or forgets to wash their hands, remember this experiment! Germs move from surfaces to people and back again. Use this lesson to start discussions about when and why to wash hands: before eating, after using the bathroom, after playing outside, and whenever hands look or feel dirty.
Learning Objectives
- Understand how germs can spread through direct contact.
- Recognize why proper handwashing is crucial for stopping the spread of germs.
- Observe and describe the transfer of “germs” (glitter) in a real-world setting.
Teacher & Parent Tips
- Encourage children to observe closely and discuss what objects or people ended up with the most glitter.
- Repeat the experiment after everyone washes their hands and compare results.
- Talk about places at home and in public where germs spread quickly (doorknobs, phones, desks, etc.).
- Make the activity fun and memorable—kids love the mess, and it’s worth it for the lesson!
Standards Alignment
NGSS 3-LS3-2: Use evidence to support the explanation that traits can be influenced by the environment.
NGSS 3-5-ETS1-2: Generate and compare multiple possible solutions to a problem based on how well they meet criteria and constraints.
Printable Worksheet
Want a ready-to-use printable version for your homeschool science lesson?

Frequently Asked Questions
Glitter makes it easy to “see” how invisible germs move from person to person and surface to surface—making the lesson memorable and visual!
Wash with soap and warm water, rubbing for at least 20 seconds. Some glitter may stick—just like stubborn germs!
Try using a bit of cooking oil or just damp hands. The lotion helps glitter stick, but it isn’t required.
Yes—just remind kids not to touch their eyes or mouth while glitter is on their hands. Supervise handwashing and cleanup.
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